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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bca4f2bd835d2be8576c1d6c64699ca661b9584f0ed980cdc27b5f6f4e80791' 
  AND token = 'NeUn1hQvE2+NvddqBPiC7N9guJpcWTHn0Nb2ZYlZ5n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}