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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c51b335ab2186980569aba0ce3b648c5c5faba783052b2ba6e88f87ae080081' 
  AND token = 'FjjQOqeij+B/uhPiJjXCZoDC1CBpWFtJW6G7oW3mISw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}