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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fbeec3ff7378e1140038fc7db06cdebffdb2f542f3480b222be2511ce3be5b' 
  AND token = 'Cd7/I0mytcQhCwlyzwIhZ9F1TpEo/bWU5xexjD0JpBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}