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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43002b3f706de9ec9046e26f5a16ebca7b2a7a7b2165103d083f7181eec187d' 
  AND token = '6nfML9jx2DBvbVFDRQmp76PJpL+rLUYjSpE8pVIkWQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}