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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287454364099775880c3f69f9829d8d74e7b14f770e03dbd8537b30b25293cee' 
  AND token = 'zJo54HyeJq+dF/AeNqbSON0ja9mNAw7Vh2RsIA6FUfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}