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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b662f782f68b7c72986f93e9f70b32ac12269c4433dd09d7e0f98169b1d654' 
  AND token = '2o/WfGdeh4YTbduwoAKty8PLxfs/sgs6OpwWQgo++mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}