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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66634536d683bf621f5806c822716e521d9c6862a94e5c2e387fd7c982a0510c' 
  AND token = 'aMJW3UByTS9mK5sR8qoawtm7Zmirgqlc5b83p5ASkx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}