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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed9616e1d3d1664d087f02c6495e8b582009c4d89c4de8a7640f22386b335f2' 
  AND token = '+ewbIzV7mkm00i94KYokzzLyzADVsOrB6ZmrBMr2g9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}