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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0509813b314649ccf4928fa6dcc5220072abad2c2210d23e53b4df8f9979ba73' 
  AND token = 'NQWalwpMOuZPmTZgAJSYDQCaJcVs2/wv0JmOHOCRkaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}