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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3eeaf5706a5a6ebb22f42aa296e5f11e5c700aa226b0b7f53be4e488b0b344a' 
  AND token = '7W4WCy2+u3bFbVn8lfC8kyoNARyBWHJhjbLjOndPtMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}