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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bdd3184a088c6c5ce04c54181f5fe2f4483de1c613844c428fcc538c4ea55b' 
  AND token = 'hUz6MoqBYy1UDIguV9bTRJggcM1dK4s4dqk1x5CsiNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}