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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0190f10d97d6d3037362423c990e2c8c19fbb2f59c2c75f687111e017f9b5ed' 
  AND token = 'HZl8o26eGzNTo2PK2X8IvVRIv78z2ogpRBCTEnQ2gsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}