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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7074d1b6ad101b0ca371b3c2857a81c0b84dd619ce3cc8d75e62bba080f9b6f7' 
  AND token = '5C+INeRy8+fC4AwLY9LSU1OD6WOZZz9c9AD+ZdBv0iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}