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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2ed03e03aa0b0fd5494b2e078aca43e2d57e03f0fc19fcf55e5161ac675e3f0' 
  AND token = 'NMzmSljtkaz3Zi/qk1xO+yTzOdBhesXYlrMyYiHNzSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}