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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed35df2e15f6787ac7298d0cc1fbbe035d4a470af3bf24071e5f92880c240100' 
  AND token = '6zUc5EDQN6XXKCiqom9vAkd30PmOnVwq8QAcqMyQKWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}