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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caeef0c9a766e465bda7467ee5ef2f8cebcf957b4badea213a7cd8cc4520f127' 
  AND token = 'ddAON4y+i8RF96NBxJQ83qLVVyCQfsrtYiuR4w2nmJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}