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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499c56225cb3a323080d96a18e6970ab7eba2dd6e877d46593bb7d889a43aa48' 
  AND token = 't2kIX/KBfZLgkPUZjcXSAlcELDtMQkaoF4YSPvzCjNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}