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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fbbd1a02bf9874d844670702cc75ebb6f5ab1e60b0162019cd472e166f2223d' 
  AND token = 'IVOyG3mHb1q6pDOp2cDLswVjiGPZqV9anwiLhodl9y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}