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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334396865a220e55bd714a062496ccb0b5587d2d83f4f8cd4664b704b2962fe5' 
  AND token = 'R2y4E2N1IE95JD/QIaXEPUUJNAmhUmAzJ+XFUQloKxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}