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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354920127a46f876555c67d3b678b1b17fbc4df1a0815ba3c01b00ead9871eff' 
  AND token = 'pk9JXP6E6U6mtQ4JnMoouqGW4LrnMQOJuMwSGcMoYQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}