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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50663367f14ceea2c3b125a7d666d61baff509144425d173074b350f6e148f6a' 
  AND token = '7yddR48ymuo+8Hw4Qkg4omonl/oLura6mvWk/3ALdLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}