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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eef1bfe18c7c2d9950502bee21c1c69b0d8aeaf5144f8d57218c91a5c68e18a' 
  AND token = 'MdzFYQsl2ibLLo6hNa3O9E8UJt4cPSBAVCOtSs3seA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}