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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b6d5be5a029d074decb7d5f16bff0af1ab2c082881eb63ca4e620c8d35c744' 
  AND token = '9G1sE1rys6PdZjCskuPyGtASlHAPx+KPVjD1Liy0CCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}