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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a1b857a2dbb2d7b6782aa58c5cd44278c8f504f02eccdd6af88c98cf5016d6' 
  AND token = 'erJtLRxoQg3c8Slk58+J6TGj/fN254c5t/t+QBnnlyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}