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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d82391ffd1af38ffd7dc27eec3a4083727b2c75f3b8396f1cfb284e3021df30' 
  AND token = 'zpHDNZ/Yz8HFTu0ZUbbRyNvvoyN7PGFTH4U0PLRpsik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}