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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cab01dbc174f8f3eadf1e12c5c6d1fe2a21d8c801bcb88daa115232d868b76f' 
  AND token = 'EJDBPn9f/M+2FiyZhnXK64+bDkFJTQy9tYwUI3TUSns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}