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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f810d2056c35eb5764f28f6c18c5486bf9b72cfb375bb176d16667ea2de85f83' 
  AND token = '66X6QEOU3frWI+Qtlu36MpM9mGTA1H/LsmaqzMxzIxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}