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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b646af113b4ab5648c6709a1cd6d70d1de8d668d8f81ff7a7a231c3de83b777' 
  AND token = 'VGUOkk6KC712QBwYoQyJZiC6D/DERiO2CvTpMZOdjs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}