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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db1db25507ccc7ee558e801fc972f4a4977106f8f0d2c3586d4bbf7730190d3' 
  AND token = '2PvUkcmxeAkNijulBsGspvlENVIT+H7cVpOT8uwDVs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}