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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb8fa98bdd881d4ffd1dc504179305aed1ab18d5ff9faf9522dfd45c07b38af' 
  AND token = 'z0e88P9SAKZBSYVwTcra5pkTS1CsGhIlT/Ef+0iRsWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}