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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fd260dcce61f6c30542bb48529520a2edd4c318043c5dea4e0e4bc83eacddc' 
  AND token = 'vDwQ4cGk+P/2X+SwJvTiCV7K/7eFEFK53JIJ1inqjf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}