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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f45f0ce0b7a1e2ed3070e7994d7b1530d117a0891a24873e300fc6e679eedd' 
  AND token = 'OJ7ljdSv3m/eDM4abX0Mbvu4icNTWBbWEgHnrggIRMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}