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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb1851bb008db1d41205ff4e6e03a3f8e7e03a9e354a63930619f6cadfac4c4' 
  AND token = '8tkJmUGAQY64petYWwLuwG2BZoWm4B5PT1STFZZ6lHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}