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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b16771c166f22d5fb0165577aff010cca865f060ce91bbf79f6a948d316e19c' 
  AND token = 'iDXfxGgqeprjg/7W5ZizsjP5bN0TUgIHHR4NqX6DOC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}