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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bb18fa3aa4c34712e736e5324aded67fd894457454fae0e9add23dbae027d5d' 
  AND token = 'PMj0XGwi4Bh21ytQ1s2dx8df9rn5ob+pawHND5J2VA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}