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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed43ea82ca5643c25df8efee8b808700105983d532f76fbb508797407d9ed2c5' 
  AND token = 'u60bJMUbqgj8B5ASgZnrpwo3rflHrUe9TRxwvpFTTXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}