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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a2e9a52cb56cdbb2f045a3c60912c77ef8ed9a95716cf90982851184a992a85' 
  AND token = 'vJQA7/HCfkoyjvOcG2UUujSHPPpZNd1zlt6GcB7JB8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}