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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '501d9d6b66aebe68937e784cbecdd766c9896da2b592cf219d5a9949f5b03cca' 
  AND token = 'POEch7bTJ57FYh2h9oo446L5kfRVS0JY1zVkM83iEo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}