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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620acf34a3356d5169401e614595c005f22714fd98154217f0fba8b3eb217449' 
  AND token = 'Sg2t342oMQuTbc11nF28sk9WpN2NyGJiqcUvBOBZ8q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}