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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428cff5c1db6dd5796851d6881016c6dd7a55f744c7d36a1f1cc32490ae116f2' 
  AND token = 'aAuZRafX3U6wd12SqMEGsvIc/MA/VpAiDx3tgcndIVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}