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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850c73a0aa6e67e93b98e31591364408a809b97644900e48c356d6c93a3f9196' 
  AND token = 'rrntjsAF/xdD5Wtln2D0Ewp8KYJ9i9a0bX9CEIwcUwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}