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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c972b0017700da4c61db9f4ddcd3aa550b6cba2b0485d53c8e7217de4469159' 
  AND token = 'yEx891u7hL20BYOyr4gR0qSmBtTVamMmyGO+Rzc+Sqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}