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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a3470cbbdb4e779c46f62d66b1d8a29ed51f51078dd16d4a15862d93f2ed38' 
  AND token = 'V+EOXX7qtNgjCjwyf6WzABv0uqwyAWeOAb7olomHdpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}