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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bdd0de9a5665719d80a84c6442ac7d91f102d03501c2a8478c6e037df975c37' 
  AND token = 'VmWLC1VV6OcW9K0yMgKOZJ5HQFy6wCuYLQnf0O07O1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}