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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e8e78bddcd28e37089f0ce9b88c213ca33d461f3fb7df6d28fc16359710a06f' 
  AND token = 'LG37yLbh3/R6yh754occq8OdTF5c6yUWJE7LwW7ShOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}