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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8829d280db3a3ee521b4d3952f4b1a09e578d594ecf8f85570431c113f727645' 
  AND token = '3HOisyRyLyK3t+SDu9bMOEsb7UmFqsVRk9YtDM33jwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}