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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb9c1418499c004006c91a732833f22c7e83d53fb3e8c834325541a98739cb8' 
  AND token = 'HCp6mKwqgy2cSrRAzja6Z9UZRvmwJe5UScdVDJlS15E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}