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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0be50013fae117e74e2155457128b586530957dd5f8f2635d0a23313a5f43c' 
  AND token = 'M7x6y8q6P06in/bT+hABKpcNfelCVllao8vI2thzGOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}