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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a7e9f25a82b572cb603a4dcf2eaa8b7f1def35e6750eb725bfc4bb95b00149' 
  AND token = '81pQ8X1LF/S5Afoky1g3zt8hhVFRGmrlVdRZX2arOxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}