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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c22c88193449b795b4f80585fc96bb18aae822958f0b445ad3c9404bf2289a' 
  AND token = '4ql/QVuPVy6Y4Z8I18UY4KWqks1in1tvgJTj5a0+ZvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}